We use the freshwater planarian (Schmidtea mediterranea) and zebrafish (Danio rerio) as model organisms to study how adult stem cells make their precise cellular lineages during neural regeneration following acute injury. We also study how this biology becomes dysregulated during the formation of brain cancers such as glioblastoma multiforme.

Our overarching goal is to understand the basic biology and molecular mechanisms of neural regeneration at a single-cell level.